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What is mononucleosis?

  • A disease that is caused by the Epstein Barr virus, which is commonly known as “mono.”

Signs and Symptoms

  • Usually mild or has no signs or symptoms in younger children.
  • Most people are infected during childhood.
  • The disease may go undiagnosed and can be rarely severe.
  • Fever
  • Sore throat
  • Fatigue
  • Swollen lymph nodes
  • Rash may occur after taking ampicillin or other penicillin treatments.

Incubation and Contagious Period

  • Incubation period usually last between 30 to 50 days.
  • Contagious period usually last for several months after infection and may occur intermittently throughout life.

How is the disease spread?

  • Person to person contact from:
    • Kissing others on the mouth
    • Sharing objects that are contaminated with saliva
    • Blood transfusions
How is the disease controlled?
  • Frequent hand washing techniques.
  • By avoiding direct contact of respiratory secretions or objects.
  • People with the disease should not donate blood or prepare food for others.

Caregiver, Teacher, and Family Roles

  • Practice good hand washing techniques at all times.
  • Clean and sanitize all children toys and utensils before use and/or shared.
  • Ensure that all children use their own toothbrush, cups, and eating utensils.
  • Avoid kissing children on the mouth in order to prevent contamination.

Group Settings

  • It is unnecessary to exclude children from group settings unless the child is unable to participate.
  • Exclude all children who are still experiencing any signs or symptoms such as fever and show a change in behavior.

When child is not showing any signs or symptoms along with normal behavior, then the child is ready to come back and participate in group settings like attending school.


Information on this site is intended for Angel Kids Pediatrics patients only. Always consult your doctor before beginning, modifying, or discontinuing any treatment plan.

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